EFSA responds to criticisms on PFAS carcinogenicity levels following inquiry

Following inquiries made by our journal regarding recent declarations made by Professor Philippe Grandjean on per- and polyfluoroalkyl substances (PFAS) and the tolerable weekly intake (TWI) established by the European Food Safety Authority (EFSA), EFSA has provided a statement addressing the concerns raised.    

Professor Grandjean, an esteemed expert in Environmental Medicine, had expressed criticism of EFSA's calculation of the TWI for PFAS in 2020, considering it erroneously high. He pointed out that the United States Environmental Protection Agency (EPA) recommended exposure limits are hundred times lower than those set by EFSA.    

In response to our inquiries, EFSA replied: “The studies conducted by Grandjean and co-authors have been taken into account in the latest EFSA opinion on PFAS and in the EPA’s 2022 assessments. Explanations regarding how these studies were considered are provided in the respective assessments. Please note that the EPA’s 2022 assessment specifically focuses on drinking water and establishes health advisories. It is important to note that in Europe, the responsibility for setting maximum levels in drinking water falls under the European Commission DG Environment and is not under the remit of EFSA.“    

The ongoing discussions and collaborations among experts, regulatory bodies, and stakeholders will continue to shape our understanding of PFAS and guide future decision-making processes. The exchange of information and perspectives will contribute to ensuring the protection of public health and the development of effective strategies to mitigate the potential risks associated with PFAS exposure.